Fig. 1

Levels of miR-23b-3p, miR-126-3p, and GAS5 in EVs from breast cancer cells after sorafenib treatment. Levels of miR-23b-3p, miR-126-3p, and GAS5 encapsulated in the EVs were determined using ddPCR technology. Concentration of each target is expressed as copies/µL. Treatment with sorafenib caused dysregulation of the level of the 3 selected ncRNAs. The graphics represent mean value; bars, SD. Unpaired t-test was used; *p < 0.05, **p < 0.01, ***p < 0.001. Results are representative of two independent experiments