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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Sos1 ablation alters focal adhesion dynamics and increases Mmp2/9-dependent gelatinase activity in primary mouse embryonic fibroblasts

Fig. 2

Sos1 depletion alters focal adhesion and F-actin distribution in primary MEFs. Representative confocal microscopy images of individual primary MEFs from the four genotypes (Sos1/2WT, Sos1KO, Sos2KO and Sos1/2DKO) stained with for actin filaments with phalloidin (green), focal adhesions (FA) with anti-Paxillin antibody (red) and for nuclei with DAPI (blue). Arrows show predominant areas of FA localization in Sos1/2WT and Sos2KO MEFs. Scale bar: 25 μm

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Cell Communication and Signaling

ISSN: 1478-811X