Fig. 7

PIEZO1 and calcium-driven translocation of TFs. A + B Quantification of YAP1 n/c ratio in cells in static conditions or exposed to 1–3 h of SS with or without treatment (Ca²⁺ free, 1 µM GsMTx4). Representative images show YAP1 depicted in blue. * depicts significant differences between control and treatment. C + D Quantification of SREBP2 n/c ratio in cells in static conditions or exposed to 1–3 h of SS with or without treatment (Ca²⁺ free, 1 µM GsMTx4). Representative images show SREBP2 depicted in magenta. * depicts significant differences between control and treatment according to t-test (* p < 0.05, ** p < 0.01, *** p < 0.001). All experiments were performed in at least 3 independent biological replicates