Fig. 4
From: IKZF1 as a potential therapeutic target for dendritic cell-mediated immunotherapy in IgA nephropathy
Identification the characteristic genes of high-low DCs DEGs for IgAN by machine learning algorithm. (A) Eight characteristic genes of LASSO. (B) Thriteen characteristic genes of SVM. (C) Eleven characteristic genes of Random Forest. (D) Venn diagram showing the optimal target genes. (E) Expression of IKZF1 and MPEG1 in GSE175759. (F) ROC curve of IKZF1 and MPEG1 in GSE175759. (G) The scatter plot shows the correlation between the proportion of dendritic cells and IKZF1 expression. (H) KEGG enrichment analysis using GSEA for IKZF1. ***P < 0.001 versus Normal