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Table 1 IC50 concentrations of mannose in WT and PMI knockout FaDu, CAL27 & CAL33 cells following a 48 h treatment period

From: Mannose and PMI depletion overcomes radiation resistance in HPV-negative head and neck cancer

Cell line

IC50 (mM)

95% CI (M)

P-value (vs. Parental)

FaDu

175.8

0-0.7

Reference

FaDu KO

8.7

0-0.03

< 0.0001

CAL27

95.85

0-0.21

Reference

CAL27 KD

11.82

0.002–0.021

< 0.0001

CAL33

100.3

0.013–0.18

Reference

CAL33 KO

5.194

0-0.014

< 0.0001